NAICS 541715 × Department of Health and Human Services

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) contracts at the Department of Health and Human Services

The Department of Health and Human Services's NAICS 541715 (Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)) market: incumbents, spending trend, set-asides and open solicitations — from FY2026 USAspending awards and live SAM.gov notices.

Contract data as of Oct 18, 2026 (USAspending) · recent coverage verified weekly

Obligated · FY2026
$275.2M
Q4 FY2026 vs prior quarter: +467%
Contract awards · FY2026
129
new awards with a start date in the window
Open opportunities
43
active on SAM.gov now
Recompetes · next 12 months
194
$2.3B in expiring contracts
Share of all NAICS 541715 spending
2.9%
Share of Department of Health and Human Services spending
3.4%
SBA small-business size standard
1,000 employees
Trend

Quarter over quarter

QuarterAwardsObligatedChange
Q1 FY20260$0—
Q2 FY20268$11.3M—
Q3 FY202617$39.5M+250%
Q4 FY2026104$224.4M+467%

Federal fiscal quarters (Q1 = Oct–Dec). Awards are counted in the quarter they start; obligations are the award's obligated amount.

Competition

Top contractors · FY2026

#ContractorObligatedAwardsShare
1LEIDOS HOLDINGS, INC.$111.7M1740.6%
2THE MITRE CORPORATION$48.0M1617.4%
3SCYNEXIS INC$18.5M16.7%
4FLOWWELL MEDICAL LLC$15.0M15.5%
5ISOLA THERAPEUTICS INC$7.5M12.7%

Registrations are rolled up to their corporate parent (USAspending parent UEI), so a company with several SAM registrations ranks once.

Set-asides

Set-aside mix

Set-aside typeObligatedShare
Small business set-aside$5.7M5.9%
8(a)$14.0M14.5%
SDVOSB$00.0%
WOSB / EDWOSB$00.0%
HUBZone$00.0%
Other (Indian economic enterprise, veteran, …)$211K0.2%
No set-aside (full & open)$77.1M79.4%

Share of obligations on awards whose set-aside type is recorded — 35% of this market's dollars. Most USAspending bulk-archive records leave the field blank, so blank awards are excluded rather than counted as full & open.

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Showing the 10 most recently posted of 43. Links open the notice on SAM.gov.

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Source: USAspending.gov contract awards (prime awards with a start date from Oct 1, 2025 through Sep 30, 2026), SAM.gov contract opportunities, and SBA size standards. Recompetes are contracts whose final end date — options included — falls in the next 12 months. Figures are recomputed when a new USAspending load lands. See our data sources.